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Biblioteca (s) : |
INIA Treinta y Tres. |
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Fecha : |
13/04/2022 |
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Actualizado : |
17/05/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
ROVIRA, P.J. |
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Afiliación : |
PABLO JUAN ROVIRA SANZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Anthelmintic treatment in growing cattle: A preliminary study on the effect of Ricobendazole on the fecal microbiome. |
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Fecha de publicación : |
2022 |
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Fuente / Imprenta : |
American Journal of Animal and Veterinary Sciences, 2022, volume 17, Issue 1, pages 77.88. OPEN ACCESS. doi: https://doi.org/10.3844/ajavsp.2022.77.88 |
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ISSN : |
1557-4563 (Online) |
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DOI : |
10.3844/ajavsp.2022.77.88 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 13-09-2021; Revised: 01-02-2022; Accepted: 02-03-2022; Published: 03-31-2022.
Corresponding author: pablorovira72@gmail.com |
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Contenido : |
There is limited information on the impact that anthelmintic treatments exert on the fecal microbiome of growing cattle. This study characterizes the composition and metabolic function of the cattle gut microbiome associated with different levels of parasite Fecal Egg Counts (FEC) and characterizes the fecal microbiome before and after ricobendazole-treatment. The hypothesis was that FEC levels and ricobendazole treatment (8 mL/animal RICOVERM 15 g) alter the fecal microbiome structure and predicted functionality. Fecal samples from Angus yearling steers (live weight: 249±19 kg) with Low-FEC (<100 epg) and High-FEC (840±207 epg) were collected at three-time points: Pre-Treatment (PRE-T) and 3- and 10-days post-treatment (POST-T3 and POST-T10, respectively). After DNA extraction, high-throughput sequencing of bacterial 16S rRNA amplicons and associated bioinformatics analyses were performed. Microbiome analysis revealed evidence of beta-diversity association with time of sampling. Samples collected post-treatment were characterized by higher microbial richness (alpha diversity) and increased abundance (P<0.05) of Alistipes (POST-T3) and Ruminococcaceae_UCG-010 (POST-T10) compared with samples PRE-T. On the other hand, Ruminococcaceae_UCG-014 and Christensenellaceae_ R-7_group genera were increased in samples from PRE-T compared with post-treatment. Predicted metagenome analysis revealed that biosynthesis of nucleotides, nucleosides, vitamins and amino acids were the metabolic pathways most affected due to ricobendazole-treatment. On the other hand, no significant differences in microbial diversity, microbiome composition and predicted metabolic pathways were observed pre-treatment between Low-FEC and High-FEC cattle. In general, these findings revealed that ricobendazole-administration altered the microbial diversity and composition in the feces of cattle, which led to changes in the metabolic pathways of the microbiome. This study provides a first known insight into the relationship between the microbiome and the exposure to ricobendazole in grazing cattle and sets a basis for the development of future studies comprising a larger number of animals and different anthelmintic drugs. MenosThere is limited information on the impact that anthelmintic treatments exert on the fecal microbiome of growing cattle. This study characterizes the composition and metabolic function of the cattle gut microbiome associated with different levels of parasite Fecal Egg Counts (FEC) and characterizes the fecal microbiome before and after ricobendazole-treatment. The hypothesis was that FEC levels and ricobendazole treatment (8 mL/animal RICOVERM 15 g) alter the fecal microbiome structure and predicted functionality. Fecal samples from Angus yearling steers (live weight: 249±19 kg) with Low-FEC (<100 epg) and High-FEC (840±207 epg) were collected at three-time points: Pre-Treatment (PRE-T) and 3- and 10-days post-treatment (POST-T3 and POST-T10, respectively). After DNA extraction, high-throughput sequencing of bacterial 16S rRNA amplicons and associated bioinformatics analyses were performed. Microbiome analysis revealed evidence of beta-diversity association with time of sampling. Samples collected post-treatment were characterized by higher microbial richness (alpha diversity) and increased abundance (P<0.05) of Alistipes (POST-T3) and Ruminococcaceae_UCG-010 (POST-T10) compared with samples PRE-T. On the other hand, Ruminococcaceae_UCG-014 and Christensenellaceae_ R-7_group genera were increased in samples from PRE-T compared with post-treatment. Predicted metagenome analysis revealed that biosynthesis of nucleotides, nucleosides, vitamins and amino acids were the metabolic... Presentar Todo |
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Palabras claves : |
ANTHELMINTIC; CATTLE; MICROBIOME; PARASITES. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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URL : |
https://www.thescipub.com/pdf/ajavsp.2022.77.88.pdf
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Marc : |
LEADER 03088naa a2200205 a 4500
001 1063029
005 2022-05-17
008 2022 bl uuuu u00u1 u #d
022 $a1557-4563 (Online)
024 7 $a10.3844/ajavsp.2022.77.88$2DOI
100 1 $aROVIRA, P.J.
245 $aAnthelmintic treatment in growing cattle$bA preliminary study on the effect of Ricobendazole on the fecal microbiome.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 13-09-2021; Revised: 01-02-2022; Accepted: 02-03-2022; Published: 03-31-2022. Corresponding author: pablorovira72@gmail.com
520 $aThere is limited information on the impact that anthelmintic treatments exert on the fecal microbiome of growing cattle. This study characterizes the composition and metabolic function of the cattle gut microbiome associated with different levels of parasite Fecal Egg Counts (FEC) and characterizes the fecal microbiome before and after ricobendazole-treatment. The hypothesis was that FEC levels and ricobendazole treatment (8 mL/animal RICOVERM 15 g) alter the fecal microbiome structure and predicted functionality. Fecal samples from Angus yearling steers (live weight: 249±19 kg) with Low-FEC (<100 epg) and High-FEC (840±207 epg) were collected at three-time points: Pre-Treatment (PRE-T) and 3- and 10-days post-treatment (POST-T3 and POST-T10, respectively). After DNA extraction, high-throughput sequencing of bacterial 16S rRNA amplicons and associated bioinformatics analyses were performed. Microbiome analysis revealed evidence of beta-diversity association with time of sampling. Samples collected post-treatment were characterized by higher microbial richness (alpha diversity) and increased abundance (P<0.05) of Alistipes (POST-T3) and Ruminococcaceae_UCG-010 (POST-T10) compared with samples PRE-T. On the other hand, Ruminococcaceae_UCG-014 and Christensenellaceae_ R-7_group genera were increased in samples from PRE-T compared with post-treatment. Predicted metagenome analysis revealed that biosynthesis of nucleotides, nucleosides, vitamins and amino acids were the metabolic pathways most affected due to ricobendazole-treatment. On the other hand, no significant differences in microbial diversity, microbiome composition and predicted metabolic pathways were observed pre-treatment between Low-FEC and High-FEC cattle. In general, these findings revealed that ricobendazole-administration altered the microbial diversity and composition in the feces of cattle, which led to changes in the metabolic pathways of the microbiome. This study provides a first known insight into the relationship between the microbiome and the exposure to ricobendazole in grazing cattle and sets a basis for the development of future studies comprising a larger number of animals and different anthelmintic drugs.
653 $aANTHELMINTIC
653 $aCATTLE
653 $aMICROBIOME
653 $aPARASITES
773 $tAmerican Journal of Animal and Veterinary Sciences, 2022, volume 17, Issue 1, pages 77.88. OPEN ACCESS. doi: https://doi.org/10.3844/ajavsp.2022.77.88
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| 3. |  | ROVIRA, P.J. Análisis integrado de los trabajos experimentales. In: ROVIRA, P.J. (Ed.). Suplementación de bovinos con grano húmedo de sorgo y fuentes proteicas sobre campo natural. Montevideo (Uruguay): INIA, 2014. p. 81-89. (INIA Serie Técnica; 212)| Tipo: Capítulo en Libro Técnico-Científico |
| Biblioteca(s): INIA Treinta y Tres. |
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| 4. | | ROVIRA, P.J. Antecedentes. In: ROVIRA, P.J. (Ed.). Uso de la sombra en la recría de novillos en sistemas pastoriles de la región Este del Uruguay. Montevideo (UY): INIA, 2012. p. 3-12 (INIA Serie Técnica; 202)| Tipo: Capítulo en Libro Técnico-Científico |
| Biblioteca(s): INIA Las Brujas; INIA Tacuarembó; INIA Treinta y Tres. |
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| 6. | | ROVIRA, P.J. Consideraciones finales. In: ROVIRA, P.J. (Ed.). Uso de la sombra en la recría de novillos en sistemas pastoriles de la región Este del Uruguay. Montevideo (UY): INIA, 2012. p. 81-82 (INIA Serie Técnica; 202)| Tipo: Capítulo en Libro Técnico-Científico |
| Biblioteca(s): INIA Las Brujas; INIA Tacuarembó; INIA Treinta y Tres. |
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| Registros recuperados : 237 | |
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